7OUF: Structure of the STLV intasome:B56 complex bound to the strand-transfer inhibitor XZ450

PDB ID: 7OUFDownload
MMDB ID: 205724
PDB Deposition Date: 2021/6/11
Updated in MMDB: 2021/10
Experimental Method:
electron microscopy
Resolution: 3  Å
Source Organism:
Simian T-lymphotropic virus 1▼
Similar Structures:
Biological Unit for 7OUF: decameric; determined by author
Molecular Components in 7OUF
Label Count Molecule
Proteins (6 molecules)
4
Integrase
Molecule annotation
2
Isoform 3 of PC4 and Sfrs1-interacting Protein,isoform Gamma-1 of Serine/threonine-protein Phosphatase 2A 56 KDA Regulatory Subunit Gamma Isoform
Molecule annotation
Nucleotides(4 molecules)
2
DNA (5'-d(*ap*cp*tp*gp*tp*gp*tp*tp*tp*gp*gp*cp*gp*cp*tp*tp*cp*tp*cp*tp*c)-3')
Molecule annotation
2
DNA (5'-d(*gp*ap*gp*ap*gp*ap*ap*gp*cp*gp*cp*cp*ap*ap*ap*cp*ap*cp*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
4
ZINC IONZINC ION
2
4
MAGNESIUM IONMAGNESIUM ION
3
2
4-azanyl-~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-6-[3-(dimethylamino)-3-oxidanylidene-propyl]-1-oxidanyl-2-oxidanylidene-1,8-naphthyridine-3-carboxamide4-azanyl-~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-6-[3-(dimethylamino)-3-oxidanylidene-propyl]-1-oxidanyl-2-oxidanylidene-1,8-naphthyridine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303