7ONT: PARP1 catalytic domain in complex with a selective pyridine carboxamide-based inhibitor (compound 22)

PDB ID: 7ONTDownload
MMDB ID: 206609
PDB Deposition Date: 2021/5/25
Updated in MMDB: 2021/11
Experimental Method:
x-ray diffraction
Resolution: 1.853  Å
Source Organism:
Similar Structures:
Biological Unit for 7ONT: monomeric; determined by author
Molecular Components in 7ONT
Label Count Molecule
Protein (1 molecule)
1
Poly [adp-ribose] Polymerase 1
(Gene symbol: PARP1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
5-[4-[(3-ethyl-2-oxidanylidene-1~{H}-quinolin-7-yl)methyl]piperazin-1-yl]-~{N}-methyl-pyridine-2-carboxamide5-[4-[(3-ethyl-2-oxidanylidene-1~{H}-quinolin-7-yl)methyl]piperazin-1-yl]-~{N}-methyl-pyridine-2-carboxamide
2
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303