7OJI: ABCG2 topotecan turnover-2 state

PDB ID: 7OJIDownload
MMDB ID: 204806
PDB Deposition Date: 2021/5/16
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.4  Å
Source Organism:
Similar Structures:
Biological Unit for 7OJI: dimeric; determined by author
Molecular Components in 7OJI
Label Count Molecule
Proteins (2 molecules)
2
Broad Substrate Specificity Atp-binding Cassette Transporter Abcg2
(Gene symbol: ABCG2)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
(S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE(S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE
2
4
CHOLESTEROLCHOLESTEROL
3
2
DIUNDECYL PHOSPHATIDYL CHOLINEDIUNDECYL PHOSPHATIDYL CHOLINE
4
2
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303