7OH7: Cryo-EM structure of Drs2p-Cdc50p in the E1-AMPPCP state with PI4P bound

PDB ID: 7OH7Download
MMDB ID: 203079
PDB Deposition Date: 2021/5/9
Updated in MMDB: 2021/06
Experimental Method:
electron microscopy
Resolution: 3.8  Å
Source Organism:
Similar Structures:
Biological Unit for 7OH7: dimeric; determined by author and by software (PISA)
Molecular Components in 7OH7
Label Count Molecule
Proteins (2 molecules)
1
Probable Phospholipid-transporting Atpase Drs2,probable Phospholipid-transporting Atpase Drs2
(Gene symbol: DRS2)
Molecule annotation
1
Cell Division Control Protein 50
(Gene symbol: CDC50)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
6
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
beta-D-mannopyranosebeta-D-mannopyranose
3
1
(2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate(2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
4
1
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
5
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303