7O4S: Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme with Coenzyme A bound at the hydratase, thiolase active sites and additional binding site (CoA(ECH2))

PDB ID: 7O4SDownload
MMDB ID: 205954
PDB Deposition Date: 2021/4/7
Updated in MMDB: 2021/09
Experimental Method:
x-ray diffraction
Resolution: 2.79  Å
Source Organism:
Similar Structures:
Biological Unit for 7O4S: tetrameric; determined by author and by software (PISA)
Molecular Components in 7O4S
Label Count Molecule
Proteins (4 molecules)
2
3-hydroxyacyl-coa Dehydrogenase
(Gene symbol: fadB)
Molecule annotation
2
Putative Acyltransferase Rv0859
(Gene symbol: Rv0859)
Molecule annotation
Chemicals and Non-standard biopolymers (38 molecules)
1
26
SULFATE IONSULFATE ION
2
4
GLYCEROLGLYCEROL
3
6
COENZYME ACOENZYME A
4
1
3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE
5
1
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303