7O1W: X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 2 (mi307) soaked at 1 M NaCl

PDB ID: 7O1WDownload
MMDB ID: 206203
PDB Deposition Date: 2021/3/30
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 7O1W: monomeric; determined by author and by software (PISA)
Molecular Components in 7O1W
Label Count Molecule
Protein (1 molecule)
1
Furin
(Gene symbol: FURIN)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
3
[[(2E)-2-[[4-[(E)-[[azaniumylidene(azanyl)methyl]hydrazinylidene]methyl]phenyl]methylidene]hydrazinyl]-azanyl-methylidene]azanium[[(2E)-2-[[4-[(E)-[[azaniumylidene(azanyl)methyl]hydrazinylidene]methyl]phenyl]methylidene]hydrazinyl]-azanyl-methylidene]azanium
2
3
CALCIUM IONCALCIUM ION
3
3
SODIUM IONSODIUM ION
4
1
CHLORIDE IONCHLORIDE ION
5
5
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
6
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303