7NYG: 14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-127

PDB ID: 7NYGDownload
MMDB ID: 203035
PDB Deposition Date: 2021/3/22
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.4  Å
Source Organism:
Similar Structures:
Biological Unit for 7NYG: tetrameric; determined by author and by software (PISA)
Molecular Components in 7NYG
Label Count Molecule
Proteins (4 molecules)
2
14-3-3 Protein Sigma
(Gene symbol: SFN)
Molecule annotation
2
Transcription Factor P65
(Gene symbol: RELA)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
4-[(2~{S})-2-methylpyrrolidin-1-yl]sulfonylbenzaldehyde4-[(2~{S})-2-methylpyrrolidin-1-yl]sulfonylbenzaldehyde
2
2
CHLORIDE IONCHLORIDE ION
3
2
MAGNESIUM IONMAGNESIUM ION
4
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303