7NXJ: Crystal structure of human Cdk13/Cyclin K in complex with the inhibitor THZ531

PDB ID: 7NXJDownload
MMDB ID: 201968
PDB Deposition Date: 2021/3/18
Updated in MMDB: 2021/05
Experimental Method:
x-ray diffraction
Resolution: 2.36  Å
Source Organism:
Similar Structures:
Biological Unit for 7NXJ: dimeric; determined by author and by software (PISA)
Molecular Components in 7NXJ
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 13
(Gene symbol: CDK13)
Molecule annotation
1
Cyclin-k
(Gene symbol: CCNK)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[4-[(3R)-3-[[5-chloranyl-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidin-1-yl]carbonylphenyl]-4-(dimethylamino)butanamideN-[4-[(3R)-3-[[5-chloranyl-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidin-1-yl]carbonylphenyl]-4-(dimethylamino)butanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303