7NTI: Structure of TAK1 in complex with compound 22

PDB ID: 7NTIDownload
MMDB ID: 200803
PDB Deposition Date: 2021/3/9
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 1.98  Å
Source Organism:
Similar Structures:
Biological Unit for 7NTI: monomeric; determined by author and by software (PISA)
Molecular Components in 7NTI
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase 7,tgf-beta-activated Kinase 1 and Map3k7-binding Protein 1
(Gene symbol: MAP3K7)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
5
GLYCEROLGLYCEROL
2
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
~{N}-[[2-[bis(fluoranyl)methoxy]phenyl]methyl]-~{N}-[2-(methylamino)-2-oxidanylidene-ethyl]-2-pyrrolidin-1-ylcarbonyl-1~{H}-imidazole-4-carboxamide~{N}-[[2-[bis(fluoranyl)methoxy]phenyl]methyl]-~{N}-[2-(methylamino)-2-oxidanylidene-ethyl]-2-pyrrolidin-1-ylcarbonyl-1~{H}-imidazole-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303