7NTH: Structure of TAK1 in complex with compound 54

PDB ID: 7NTHDownload
MMDB ID: 200802
PDB Deposition Date: 2021/3/9
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 1.97  Å
Source Organism:
Similar Structures:
Biological Unit for 7NTH: monomeric; determined by author
Molecular Components in 7NTH
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase Kinase Kinase 7,tgf-beta-activated Kinase 1 and Map3k7-binding Protein 1
(Gene symbol: MAP3K7)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
GLYCEROLGLYCEROL
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
2-[[5-[[2-[bis(fluoranyl)methoxy]phenyl]methyl-[(2~{R})-1-(methylamino)-1-oxidanylidene-propan-2-yl]carbamoyl]-1~{H}-imidazol-2-yl]carbonyl]isoindole-5-carboxamide2-[[5-[[2-[bis(fluoranyl)methoxy]phenyl]methyl-[(2~{R})-1-(methylamino)-1-oxidanylidene-propan-2-yl]carbamoyl]-1~{H}-imidazol-2-yl]carbonyl]isoindole-5-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303