7NR4: X-RAY STRUCTURE OF PRMT6 IN COMPLEX WITH indazole type inhibitor

PDB ID: 7NR4Download
MMDB ID: 200801
PDB Deposition Date: 2021/3/2
Updated in MMDB: 2025/12
Experimental Method:
x-ray diffraction
Resolution: 2.03  Å
Source Organism:
Similar Structures:
Biological Unit for 7NR4: dimeric; determined by author and by software (PISA)
Molecular Components in 7NR4
Label Count Molecule
Proteins (2 molecules)
2
Protein Arginine N-methyltransferase 6
(Gene symbol: PRMT6)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
2
2
(2~{S})-2-azanyl-~{N}-[3-[3-(dimethylsulfamoyl)phenyl]-2~{H}-indazol-5-yl]propanamide(2~{S})-2-azanyl-~{N}-[3-[3-(dimethylsulfamoyl)phenyl]-2~{H}-indazol-5-yl]propanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303