7NNS: Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound Momelotinib

PDB ID: 7NNSDownload
MMDB ID: 200795
PDB Deposition Date: 2021/2/25
Updated in MMDB: 2021/04
Experimental Method:
x-ray diffraction
Resolution: 2.14  Å
Source Organism:
Similar Structures:
Biological Unit for 7NNS: monomeric; determined by author and by software (PISA)
Molecular Components in 7NNS
Label Count Molecule
Protein (1 molecule)
1
Activin Receptor Type I
(Gene symbol: ACVR1)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
MomelotinibMomelotinib
3
7
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303