7NBQ: Co-crystal structure of Human Nicotinamide N-methyltransferase (NNMT) with the tricyclic inhibitor (4)

PDB ID: 7NBQDownload
MMDB ID: 200019
PDB Deposition Date: 2021/1/27
Updated in MMDB: 2025/12
Experimental Method:
x-ray diffraction
Resolution: 2.479  Å
Source Organism:
Similar Structures:
Biological Unit for 7NBQ: monomeric; determined by author and by software (PISA)
Molecular Components in 7NBQ
Label Count Molecule
Protein (1 molecule)
1
Nicotinamide N-methyltransferase
(Gene symbol: NNMT)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
2
1
2-methyl-1,2,6,7-tetrahydro-3H,5H-pyrido[3,2,1-ij]quinazolin-3-imine2-methyl-1,2,6,7-tetrahydro-3H,5H-pyrido[3,2,1-ij]quinazolin-3-imine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303