7NBJ: Co-crystal structure of Human Nicotinamide N-methyltransferase (NNMT) with the bisubstrate-like inhibitor (1)

PDB ID: 7NBJDownload
MMDB ID: 200017
PDB Deposition Date: 2021/1/27
Updated in MMDB: 2021/03
Experimental Method:
x-ray diffraction
Resolution: 2.275  Å
Source Organism:
Similar Structures:
Biological Unit for 7NBJ: monomeric; determined by author and by software (PISA)
Molecular Components in 7NBJ
Label Count Molecule
Protein (1 molecule)
1
Nicotinamide N-methyltransferase
(Gene symbol: NNMT)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
2-hydroxy-1-(4-(isoquinolin-5-yl)piperazin-1-yl)-2-methyl-3-(3-methyl-4-phenyl-1H-pyrazol-1-yl)propan-1-one2-hydroxy-1-(4-(isoquinolin-5-yl)piperazin-1-yl)-2-methyl-3-(3-methyl-4-phenyl-1H-pyrazol-1-yl)propan-1-one
2
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303