7N7O: Crystal Structure of PI5P4KIIAlpha complex with Palbociclib

PDB ID: 7N7ODownload
MMDB ID: 203837
PDB Deposition Date: 2021/6/10
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 7N7O: dimeric; determined by author and by software (PISA)
Molecular Components in 7N7O
Label Count Molecule
Proteins (2 molecules)
2
Phosphatidylinositol 5-phosphate 4-kinase Type-2 Alpha
(Gene symbol: PIP4K2A)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE
2
4
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303