7N7M: Crystal Structure of PI5P4KIIAlpha complex with BI-2536

PDB ID: 7N7MDownload
MMDB ID: 203835
PDB Deposition Date: 2021/6/10
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 7N7M: dimeric; determined by author and by software (PISA)
Molecular Components in 7N7M
Label Count Molecule
Proteins (2 molecules)
2
Phosphatidylinositol 5-phosphate 4-kinase Type-2 Alpha
(Gene symbol: PIP4K2A)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide
2
6
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303