7N4V: Structure of cholesterol-bound human NPC1L1

PDB ID: 7N4VDownload
MMDB ID: 206181
PDB Deposition Date: 2021/6/4
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 3.58  Å
Source Organism:
Similar Structures:
Biological Unit for 7N4V: dimeric; determined by author
Molecular Components in 7N4V
Label Count Molecule
Proteins (2 molecules)
2
Isoform 2 of Npc1-like Intracellular Cholesterol Transporter 1
(Gene symbol: NPC1L1)
Molecule annotation
Chemicals and Non-standard biopolymers (28 molecules)
1
20
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
6
CHOLESTEROLCHOLESTEROL
3
2
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303