7N42: Crystal structure of the tandem bromodomain of human TAF1 (TAF1-T) bound to ZS1-681

PDB ID: 7N42Download
MMDB ID: 203011
PDB Deposition Date: 2021/6/3
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 7N42: monomeric; determined by author and by software (PISA)
Molecular Components in 7N42
Label Count Molecule
Protein (1 molecule)
1
Transcription Initiation Factor Tfiid Subunit 1
(Gene symbol: TAF1)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
6-(but-3-en-1-yl)-4-[6-{1-[(R)-S-methanesulfonimidoyl]cyclopropyl}-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one6-(but-3-en-1-yl)-4-[6-{1-[(R)-S-methanesulfonimidoyl]cyclopropyl}-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303