7MTR: CryoEM Structure of Full-Length mGlu2 Bound to Ago-PAM ADX55164 and Glutamate

PDB ID: 7MTRDownload
MMDB ID: 206245
PDB Deposition Date: 2021/5/13
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 7MTR: dimeric; determined by author
Molecular Components in 7MTR
Label Count Molecule
Proteins (2 molecules)
2
Metabotropic Glutamate Receptor 2
(Gene symbol: GRM2)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
GLUTAMIC ACIDGLUTAMIC ACID
2
2
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
3
1
2-methoxy-6-propyl-N-(2-{4-[(1H-tetrazol-5-yl)methoxy]phenyl}ethyl)thieno[2,3-d]pyrimidin-4-amine2-methoxy-6-propyl-N-(2-{4-[(1H-tetrazol-5-yl)methoxy]phenyl}ethyl)thieno[2,3-d]pyrimidin-4-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303