7MBU: Cryo-EM structure of zebrafish TRPM5 E337A mutant in the presence of 5 mM calcium (high calcium occupancy in the transmembrane domain)

PDB ID: 7MBUDownload
MMDB ID: 204134
PDB Deposition Date: 2021/4/1
Updated in MMDB: 2021/07
Experimental Method:
electron microscopy
Source Organism:
Similar Structures:
Biological Unit for 7MBU: tetrameric; determined by author
Molecular Components in 7MBU
Label Count Molecule
Proteins (4 molecules)
4
Transient Receptor Potential Melastatin 5
(Gene symbol: trpm5)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
CALCIUM IONCALCIUM ION
3
4
(2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside(2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside
4
4
(25R)-14beta,17beta-spirost-5-en-3beta-ol(25R)-14beta,17beta-spirost-5-en-3beta-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303