7M4T: Menin bound to M-1121

PDB ID: 7M4TDownload
MMDB ID: 205528
PDB Deposition Date: 2021/3/22
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.74  Å
Source Organism:
Similar Structures:
Biological Unit for 7M4T: monomeric; determined by author and by software (PISA)
Molecular Components in 7M4T
Label Count Molecule
Protein (1 molecule)
1
Menin
(Gene symbol: MEN1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
methyl {(1S,2R)-2-[(1S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-{1-[(3-methoxy-1-{4-[(1S,4S)-5-propanoyl-2,5-diazabicyclo[2.2.1]heptane-2-sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}ethyl]cyclopentyl}carbamatemethyl {(1S,2R)-2-[(1S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-{1-[(3-methoxy-1-{4-[(1S,4S)-5-propanoyl-2,5-diazabicyclo[2.2.1]heptane-2-sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}ethyl]cyclopentyl}carbamate
2
5
praseodymium triacetatepraseodymium triacetate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303