7M40: Discovery of small molecule antagonists of human Retinoblastoma Binding Protein 4 (RBBP4)

PDB ID: 7M40Download
MMDB ID: 201947
PDB Deposition Date: 2021/3/19
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.88  Å
Source Organism:
Similar Structures:
Biological Unit for 7M40: monomeric; determined by author
Molecular Components in 7M40
Label Count Molecule
Protein (1 molecule)
1
Histone-binding Protein Rbbp4
(Gene symbol: RBBP4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N~3~-{4-[3-(dimethylamino)pyrrolidin-1-yl]-6,7-dimethoxyquinazolin-2-yl}-N~1~,N~1~-dimethylpropane-1,3-diamineN~3~-{4-[3-(dimethylamino)pyrrolidin-1-yl]-6,7-dimethoxyquinazolin-2-yl}-N~1~,N~1~-dimethylpropane-1,3-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303