7M3G: Asymmetric Activation of the Calcium Sensing Receptor Homodimer

PDB ID: 7M3GDownload
MMDB ID: 203817
PDB Deposition Date: 2021/3/18
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 7M3G: tetrameric; determined by author
Molecular Components in 7M3G
Label Count Molecule
Proteins (2 molecules)
2
Extracellular Calcium-sensing Receptor
(Gene symbol: CASR)
Molecule annotation
Chemicals and Non-standard biopolymers (25 molecules)
CD
2
etelcalcetide
1
13
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]ethanoic acid2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]ethanoic acid
3
2
TRYPTOPHANTRYPTOPHAN
4
4
CALCIUM IONCALCIUM ION
5
2
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303