7M3E: Asymmetric Activation of the Calcium Sensing Receptor Homodimer

PDB ID: 7M3EDownload
MMDB ID: 203815
PDB Deposition Date: 2021/3/18
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 7M3E: dimeric; determined by author
Molecular Components in 7M3E
Label Count Molecule
Proteins (2 molecules)
2
Extracellular Calcium-sensing Receptor
(Gene symbol: CASR)
Molecule annotation
Chemicals and Non-standard biopolymers (21 molecules)
1
11
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile
3
2
TRYPTOPHANTRYPTOPHAN
4
4
CALCIUM IONCALCIUM ION
5
2
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303