7M0M: HPK1 IN COMPLEX WITH COMPOUND 1

PDB ID: 7M0MDownload
MMDB ID: 200769
PDB Deposition Date: 2021/3/11
Updated in MMDB: 2021/05
Experimental Method:
x-ray diffraction
Resolution: 1.93  Å
Source Organism:
Similar Structures:
Biological Unit for 7M0M: dimeric; determined by author and by software (PISA)
Molecular Components in 7M0M
Label Count Molecule
Proteins (2 molecules)
2
Mitogen-activated Protein Kinase Kinase Kinase Kinase 1
(Gene symbol: MAP4K1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
4-[2-fluoro-6-(trifluoromethyl)anilino]-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide4-[2-fluoro-6-(trifluoromethyl)anilino]-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303