7LYB: Cryo-EM structure of the human nucleosome core particle in complex with BRCA1-BARD1-UbcH5c

PDB ID: 7LYBDownload
MMDB ID: 204975
PDB Deposition Date: 2021/3/6
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.28  Å
Source Organism:
Similar Structures:
Biological Unit for 7LYB: tridecameric; determined by author
Molecular Components in 7LYB
Label Count Molecule
Proteins (11 molecules)
2
Histone H3.1
(Gene symbol: H3C1)
Molecule annotation
2
Histone H4
(Gene symbol: H4C9)
Molecule annotation
2
Histone H2B Type 1-J
(Gene symbol: H2BC11)
Molecule annotation
1
Isoform 7 of Breast Cancer Type 1 Susceptibility Protein
(Gene symbol: BRCA1)
Molecule annotation
1
Ubiquitin-conjugating Enzyme E2 D3
(Gene symbol: UBE2D3)
Molecule annotation
1
Brca1-associated Ring Domain Protein 1
(Gene symbol: BARD1)
Molecule annotation
2
Histone H2A Type 1-b/e
(Gene symbol: H2AC8)
Molecule annotation
Nucleotides(2 molecules)
1
DNA (147-mer)
Molecule annotation
1
DNA (146-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303