7LTL: STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH AN INHIBITOR LACKING A ZINC BINDING GROUP (COMPOUND 19)

PDB ID: 7LTLDownload
MMDB ID: 201681
PDB Deposition Date: 2021/2/19
Updated in MMDB: 2021/05
Experimental Method:
x-ray diffraction
Resolution: 1.49  Å
Source Organism:
Similar Structures:
Biological Unit for 7LTL: monomeric; determined by author and by software (PISA)
Molecular Components in 7LTL
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 2
(Gene symbol: HDAC2)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
ZINC IONZINC ION
2
4
SULFATE IONSULFATE ION
3
2
CALCIUM IONCALCIUM ION
4
1
ACETATE IONACETATE ION
5
3
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
6
1
(2R)-2-(5-hydroxy-2-methyl-1H-indol-3-yl)-N-{(1S)-1-[5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl]pentyl}propanamide(2R)-2-(5-hydroxy-2-methyl-1H-indol-3-yl)-N-{(1S)-1-[5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl]pentyl}propanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303