7LRD: Cryo-EM of the SLFN12-PDE3A complex: Consensus subset model

PDB ID: 7LRDDownload
MMDB ID: 202984
PDB Deposition Date: 2021/2/16
Updated in MMDB: 2021/07
Experimental Method:
electron microscopy
Resolution: 3.22  Å
Source Organism:
Similar Structures:
Biological Unit for 7LRD: tetrameric; determined by author
Molecular Components in 7LRD
Label Count Molecule
Proteins (4 molecules)
2
Schlafen Family Member 12
(Gene symbol: SLFN12)
Molecule annotation
2
Cgmp-inhibited 3',5'-cyclic Phosphodiesterase a
(Gene symbol: PDE3A)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
ZINC IONZINC ION
2
2
MANGANESE (II) IONMANGANESE (II) ION
3
2
MAGNESIUM IONMAGNESIUM ION
4
2
(4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one(4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303