7LHZ: K. pneumoniae Topoisomerase IV (ParE-ParC) in complex with DNA and (3S)-10-[(3R)-3-(1-aminocyclopropyl)pyrrolidin-1-yl]-9-fluoro-3-methyl-5-oxo-2,3-dihydro-5H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid (compound 25)

PDB ID: 7LHZDownload
MMDB ID: 201926
PDB Deposition Date: 2021/1/26
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 7LHZ: hexameric; determined by software (PISA)
Molecular Components in 7LHZ
Label Count Molecule
Proteins (2 molecules)
2
DNA Topoisomerase 4 Subunit B, DNA Topoisomerase 4 Subunit a Chimera
Molecule annotation
Nucleotides(4 molecules)
2
DNA (5'-d(p*tp*ap*cp*gp*tp*tp*gp*tp*ap*t)-3')
Molecule annotation
2
DNA (5'-d(*gp*ap*tp*cp*ap*tp*ap*cp*ap*ap*cp*gp*tp*ap*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
(4S)-2-METHYL-2,4-PENTANEDIOL(4S)-2-METHYL-2,4-PENTANEDIOL
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
(3S)-10-[(3R)-3-(1-aminocyclopropyl)pyrrolidin-1-yl]-9-fluoro-3-methyl-5-oxo-2,3-dihydro-5H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid(3S)-10-[(3R)-3-(1-aminocyclopropyl)pyrrolidin-1-yl]-9-fluoro-3-methyl-5-oxo-2,3-dihydro-5H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303