7LEP: The composite LBD-TMD structure combined from all hippocampal AMPAR subtypes at 3.25 Angstrom resolution

PDB ID: 7LEPDownload
MMDB ID: 201925
PDB Deposition Date: 2021/1/14
Updated in MMDB: 2021/07
Experimental Method:
electron microscopy
Resolution: 3.25  Å
Source Organism:
Similar Structures:
Biological Unit for 7LEP: octameric; determined by author
Molecular Components in 7LEP
Label Count Molecule
Proteins (8 molecules)
1
MIX of Ampar Subunits (Glua1, Glua3, and Glua4)
Molecule annotation
2
Glutamate Receptor 2
Molecule annotation
1
MIX of Ampar Subunits (Glua1, Glua3, and Gluax)
Molecule annotation
2
Protein Cornichon Homolog 2
(Gene symbol: Cnih2)
Molecule annotation
2
Voltage-dependent Calcium Channel Gamma-8 Subunit
(Gene symbol: Cacng8)
Molecule annotation
Chemicals and Non-standard biopolymers (42 molecules)
1
4
{[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid{[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
2
30
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
3
1
TETRADECANETETRADECANE
4
1
DECANEDECANE
5
2
6-[2-chloro-6-(trifluoromethoxy)phenyl]-1H-benzimidazol-2-ol6-[2-chloro-6-(trifluoromethoxy)phenyl]-1H-benzimidazol-2-ol
6
2
N-OCTANEN-OCTANE
7
2
DODECANEDODECANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303