7LEM: Crystal structure of the first bromodomain (BD1) of human BRDT bound to LRRK2-IN-1

PDB ID: 7LEMDownload
MMDB ID: 204530
PDB Deposition Date: 2021/1/14
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 1.89  Å
Source Organism:
Similar Structures:
Biological Unit for 7LEM: monomeric; determined by author
Molecular Components in 7LEM
Label Count Molecule
Protein (1 molecule)
1
Bromodomain Testis-specific Protein
(Gene symbol: BRDT)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
2-[(2-methoxy-4-{[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl}phenyl)amino]-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one2-[(2-methoxy-4-{[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl}phenyl)amino]-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
2
5
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303