7LEJ: Crystal structure of the second bromodomain (BD2) of human BRDT bound to Volasertib

PDB ID: 7LEJDownload
MMDB ID: 204527
PDB Deposition Date: 2021/1/14
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 1.73  Å
Source Organism:
Similar Structures:
Biological Unit for 7LEJ: monomeric; determined by author and by software (PISA)
Molecular Components in 7LEJ
Label Count Molecule
Protein (1 molecule)
1
Bromodomain Testis-specific Protein
(Gene symbol: BRDT)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7R)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamideN-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7R)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303