7LCP: N-terminal finger stabilizes feline drug GC376 in coronavirus 3CL protease

PDB ID: 7LCPDownload
MMDB ID: 201921
PDB Deposition Date: 2021/1/11
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 7LCP: dimeric; determined by software (PISA)
Molecular Components in 7LCP
Label Count Molecule
Proteins (2 molecules)
2
3c-like Proteinase
(Gene symbol: orf1ab)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamideN~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
2
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
4
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303