7LBT: Crystal structure of the second bromodomain (BD2) of human BRD3 bound to ERK5-IN-1

PDB ID: 7LBTDownload
MMDB ID: 204526
PDB Deposition Date: 2021/1/8
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 7LBT: monomeric; determined by author
Molecular Components in 7LBT
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 3
(Gene symbol: BRD3)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
11-cyclopentyl-2-({2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one11-cyclopentyl-2-({2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303