7LB0: Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-295

PDB ID: 7LB0Download
MMDB ID: 204522
PDB Deposition Date: 2021/1/7
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.33  Å
Source Organism:
Similar Structures:
Biological Unit for 7LB0: monomeric; determined by author
Molecular Components in 7LB0
Label Count Molecule
Protein (1 molecule)
1
Transcription Initiation Factor Tfiid Subunit 1
(Gene symbol: TAF1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
1-{6-[(3R)-3-methylmorpholin-4-yl]-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl}cyclopropane-1-sulfonamide1-{6-[(3R)-3-methylmorpholin-4-yl]-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl}cyclopropane-1-sulfonamide
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303