7LAY: Crystal structure of the first bromodomain (BD1) of human BRD3 bound to SG3-179

PDB ID: 7LAYDownload
MMDB ID: 204520
PDB Deposition Date: 2021/1/7
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 1.45  Å
Source Organism:
Similar Structures:
Biological Unit for 7LAY: monomeric; determined by author
Molecular Components in 7LAY
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 3
(Gene symbol: BRD3)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
4-[[4-[[3-(~{tert}-butylsulfonylamino)-4-chloranyl-phenyl]amino]-5-methyl-pyrimidin-2-yl]amino]-2-fluoranyl-~{N}-(1-methylpiperidin-4-yl)benzamide4-[[4-[[3-(~{tert}-butylsulfonylamino)-4-chloranyl-phenyl]amino]-5-methyl-pyrimidin-2-yl]amino]-2-fluoranyl-~{N}-(1-methylpiperidin-4-yl)benzamide
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303