7L9T: Crystal Structure of Dihydrofolate reductase from Mycolicibacterium smegmatis in complex with SDDC-0001565 inhibitor

PDB ID: 7L9TDownload
MMDB ID: 197821
PDB Deposition Date: 2021/1/5
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 7L9T: monomeric; determined by author and by software (PISA)
Molecular Components in 7L9T
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
(Gene symbol: folA)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
3-(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid3-(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid
2
2
SULFATE IONSULFATE ION
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303