7L9K: Crystal structure of the second bromodomain (BD2) of human BRD2 bound to LRRK2-IN-1

PDB ID: 7L9KDownload
MMDB ID: 204116
PDB Deposition Date: 2021/1/4
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 7L9K: monomeric; determined by author and by software (PISA)
Molecular Components in 7L9K
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 2
(Gene symbol: BRD2)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
1,4-BUTANEDIOL1,4-BUTANEDIOL
2
2
2-[(2-methoxy-4-{[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl}phenyl)amino]-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one2-[(2-methoxy-4-{[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl}phenyl)amino]-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303