7L9J: Crystal structure of the second bromodomain (BD2) of human BRD2 bound to Ro3280

PDB ID: 7L9JDownload
MMDB ID: 204115
PDB Deposition Date: 2021/1/4
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 7L9J: monomeric; determined by author
Molecular Components in 7L9J
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 2
(Gene symbol: BRD2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide
2
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303