7L73: Crystal structure of the first bromodomain (BD1) of human BRDT bound to ERK5-IN-1

PDB ID: 7L73Download
MMDB ID: 203797
PDB Deposition Date: 2020/12/25
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 1.46  Å
Source Organism:
Similar Structures:
Biological Unit for 7L73: monomeric; determined by author and by software (PISA)
Molecular Components in 7L73
Label Count Molecule
Protein (1 molecule)
1
Bromodomain Testis-specific Protein
(Gene symbol: BRDT)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
11-cyclopentyl-2-({2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one11-cyclopentyl-2-({2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303