7L25: HPK1 IN COMPLEX WITH COMPOUND 18

PDB ID: 7L25Download
MMDB ID: 199989
PDB Deposition Date: 2020/12/16
Updated in MMDB: 2024/04
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 7L25: monomeric; determined by author
Molecular Components in 7L25
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase Kinase Kinase Kinase 1
(Gene symbol: MAP4K1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
6-(2-fluoro-6-methoxyphenyl)-1-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]-1H-pyrazolo[4,3-c]pyridine6-(2-fluoro-6-methoxyphenyl)-1-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]-1H-pyrazolo[4,3-c]pyridine
2
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303