7L1V: Orexin Receptor 2 (OX2R) in Complex with G Protein and Small-Molecule Agonist Compound 1

PDB ID: 7L1VDownload
MMDB ID: 198673
PDB Deposition Date: 2020/12/15
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 3  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 7L1V: hexameric; determined by author
Molecular Components in 7L1V
Label Count Molecule
Proteins (6 molecules)
1
Engineered Guanine Nucleotide-binding Protein Subunit Alpha
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Single-chain Antibody FV Fragment (Svfv16)
Molecule annotation
1
Hypocretin Receptor Type 2
Molecule annotation
1
Synthetic Nanobody 51 (Sb51)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4'-methoxy-N,N-dimethyl-3'-{[3-(2-{[2-(2H-1,2,3-triazol-2-yl)benzene-1-carbonyl]amino}ethyl)phenyl]sulfamoyl}[1,1'-biphenyl]-3-carboxamide4'-methoxy-N,N-dimethyl-3'-{[3-(2-{[2-(2H-1,2,3-triazol-2-yl)benzene-1-carbonyl]amino}ethyl)phenyl]sulfamoyl}[1,1'-biphenyl]-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303