7L0E: Crystal structure of bovine RPE65 in complex with gem-difluoro emixustat and palmitate

PDB ID: 7L0EDownload
MMDB ID: 202687
PDB Deposition Date: 2020/12/11
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 7L0E: dimeric; determined by author and by software (PISA)
Molecular Components in 7L0E
Label Count Molecule
Proteins (2 molecules)
2
Retinoid Isomerohydrolase
(Gene symbol: RPE65)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
FE (II) IONFE (II) ION
2
2
PALMITIC ACIDPALMITIC ACID
3
2
(1R)-3-amino-1-{3-[(4,4-difluorocyclohexyl)methoxy]phenyl}propan-1-ol(1R)-3-amino-1-{3-[(4,4-difluorocyclohexyl)methoxy]phenyl}propan-1-ol
4
1
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303