7KWE: Crystal structure of the catalytic domain of human PDE3A bound to DNMDP

PDB ID: 7KWEDownload
MMDB ID: 203194
PDB Deposition Date: 2020/11/30
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 7KWE: dimeric; determined by author
Molecular Components in 7KWE
Label Count Molecule
Proteins (2 molecules)
2
Cgmp-inhibited 3',5'-cyclic Phosphodiesterase a
(Gene symbol: PDE3A)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
(4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one(4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one
2
2
MANGANESE (II) IONMANGANESE (II) ION
3
2
MAGNESIUM IONMAGNESIUM ION
4
2
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303