7KRF: Crystal Structure of HIV-1 Reverse Transcriptase in Complex with (E)-4-(3-(2-cyanovinyl)-5-fluorophenoxy)-3-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenyl sulfurofluoridate (JLJ710)

PDB ID: 7KRFDownload
MMDB ID: 197616
PDB Deposition Date: 2020/11/19
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 7KRF: dimeric; determined by author and by software (PISA)
Molecular Components in 7KRF
Label Count Molecule
Proteins (2 molecules)
1
Hiv-1 Reverse Transcriptase, P66 Subunit
Molecule annotation
1
Hiv-1 Reverse Transcriptase, P51 Subunit
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-{3-[(E)-2-cyanoethenyl]-5-fluorophenoxy}-3-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenyl sulfurofluoridate4-{3-[(E)-2-cyanoethenyl]-5-fluorophenoxy}-3-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenyl sulfurofluoridate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303