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7KR5: Cryo-EM structure of the CRAC channel Orai in an open conformation; H206A gain-of-function mutation in complex with an antibody

PDB ID:

MMDB ID:

196297

PDB Deposition Date:

2020/11/18

Updated in MMDB:

2025/05

Experimental Method:

electron microscopy

Resolution:

3.3 Å

Source Organism:

Mus musculus▼

Taxonomy	Molecule
Mus musculus	H, L, M, N, O, P
Drosophila melanogaster	A, B, C, D, E, F

Similar Structures:

Biological Unit for 7KR5: dodecameric; determined by author

Molecular Components in 7KR5
Label	Count	Molecule
Proteins (12 molecules)
A B C D E F	6	Calcium Release-activated Calcium Channel Protein 1
H M O	3	19b5 FAB Heavy Chain
L N P	3	19b5 FAB Light Chain
Chemical and Non-standard biopolymers (1 molecule)
1	1	CALCIUM ION

* Click molecule labels to explore molecular sequence information.

Citing MMDB