7KQU: A 1.58-A resolution crystal structure of ferric-hydroperoxo intermediate of L-tyrosine hydroxylase in complex with 3-fluoro-L-tyrosine

PDB ID: 7KQUDownload
MMDB ID: 200477
PDB Deposition Date: 2020/11/17
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.579  Å
Source Organism:
Similar Structures:
Biological Unit for 7KQU: dimeric; determined by author and by software (PISA)
Molecular Components in 7KQU
Label Count Molecule
Proteins (2 molecules)
2
Heme-dependent L-tyrosine Hydroxylase
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
3
2
3-FLUOROTYROSINE3-FLUOROTYROSINE
4
2
HYDROGEN PEROXIDEHYDROGEN PEROXIDE
5
1
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303