7KPG: Blocking Fab 25 anti-SIRP-alpha antibody in complex with SIRP-alpha Variant 1

PDB ID: 7KPGDownload
MMDB ID: 196663
PDB Deposition Date: 2020/11/11
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.27  Å
Source Organism:
Similar Structures:
Biological Unit for 7KPG: trimeric; determined by author and by software (PISA)
Molecular Components in 7KPG
Label Count Molecule
Proteins (3 molecules)
1
Heavy Chain of FAB 25 Anti-sirp-alpha Antibody
Molecule annotation
1
Light Chain of FAB 25 Anti-sirp-alpha Antibody
Molecule annotation
1
Tyrosine-protein Phosphatase Non-receptor Type Substrate 1
(Gene symbol: SIRPA)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
5
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303