7KKN: Structure of the catalytic domain of tankyrase 1 in complex with talazoparib

PDB ID: 7KKNDownload
MMDB ID: 197188
PDB Deposition Date: 2020/10/27
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.48  Å
Source Organism:
Similar Structures:
Biological Unit for 7KKN: monomeric; determined by author and by software (PISA)
Molecular Components in 7KKN
Label Count Molecule
Protein (1 molecule)
1
Poly [adp-ribose] Polymerase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
ZINC IONZINC ION
2
1
(8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one(8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one
3
2
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303