7KJS: Crystal structure of CDK2/cyclin E in complex with PF-06873600

PDB ID: 7KJSDownload
MMDB ID: 203484
PDB Deposition Date: 2020/10/26
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.187  Å
Source Organism:
Similar Structures:
Biological Unit for 7KJS: dimeric; determined by author and by software (PISA)
Molecular Components in 7KJS
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 2
(Gene symbol: CDK2)
Molecule annotation
1
G1/s-specific Cyclin-e1
(Gene symbol: CCNE1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-{[1-(methylsulfonyl)piperidin-4-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-{[1-(methylsulfonyl)piperidin-4-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303